Vaccination

Field Vaccine Efficacy

Notation: EPI -Epidemic Index; FVE - Field Vaccine Efficacy.

FVE: New results.

19 March 2021.

Now we present several results on Field Vaccine Efficacy based on comparisons of epidemic waves.

Result 1: UK. Comparison of 2 waves via daily new Covid cases. FVE=0.63

Wave 1: 17 April (peak) - 23 June 2020.

Wave 2: 9 January (peak) - 18 March 2021.

Result 2: USA. Comparison of 2 waves via daily new death Covid cases. FVE=0.69

Wave 1: 17 April - 20 June 2020

Wave 2: 12 January - 16 March 2021.

UK R number/EPI graphs

FVE for the selected countries

28 February 2021

20 February 2021

14 February 2021

Further analysis of R/EPI numbers (Israel, UAE, UK and USA) for 14 Jan - 12 Feb 2021 supports that Field Vaccine Efficacy/FVE is around 0.7.

02 February 2021

Preliminary analysis of R/EPI numbers (Israel, UAE, UK and USA) for 15-29 Jan 2021 shows that the field vaccine efficacy FVE is around 0.75 (see Table below).

Vaccination coverage

14 February 2021

Further analysis of FVE/Field Vaccine Efficacy (which is around 0.7) supports that the required vaccination coverage should be at least 70%.

02 February 2021

The preliminary analysis of FVE/Field Vaccine Efficacy (which is around 0.75) suggests that the required vaccination coverage should be at least 70%.

References

The analysis is based on the research conducted in:

Becker, N. , Lefevre, Cl. and Utev, S. (2007). Estimating protective vaccine efficacy from large trials with recruitment. Statistical Planning and Inference. 137, 907-914. Available at www.sciencedirect.com/science/article/abs/pii/S0378375806001509

Becker, N.G. and Utev, S. (2002). Protective vaccine efficacy when vaccine response is random. Biometrical Journal. 44, 29-42. Available at onlinelibrary.wiley.com/doi/abs/10.1002/1521-4036(200201)44:1%3C29::AID-BIMJ29%3E3.0.CO;2-8

Vaccination data used in analysis are taken from the Our World in Data website..

EPI Graphs