• Designed and orchestrated a diagnostic procedure to vet 100+ pH probes consequently increasing lab workflow efficiency and reducing expenditures.

• Analyzed graphical representations acquired from JMP, PI Vision, and DeltaV of 3 sets of cell culture data spanning various stages of a development and pilot plant runs of a molecule.

• Constructed time course profiles of 5 metabolites, 4 key process indicators, and 4 on-line controls of a novel molecule and conducted subsequent statistical analyses including one-way ANOVAs and Tukey-Kramer tests.

• Performed small scale and pilot plant operations including clean-in-place operations, steam-in-place operations, media batching and preparation, bioreactor set up, passages in shake flasks and spinners, 2L and 20L soleras, monitoring cell culture trends, and assisted in pH off-gas reference curve generation and interpretation.

• Assisted in protein purification set-up processes including column packing and cleaning, column integrity tests, buffer preparation, and slurry ratio calculations.

• Directed the collection of ~400 upstream and downstream product retains and coordinated their international shipment to Penzberg, Germany and to Basel, Switzerland.

• Coordinated on-site vendor visits to collaborate for improvements to lab equipment operations and maintenance.

• Moderated team meetings and presented experimental data, outcomes, and future directions for an independently led pH probe project.

• Collaborated with Process Sciences team on various lab operations including sampling, continuous trends and data monitoring to ensure efficiency and productivity during operations to optimize process performance.

• Spearheaded R&D efforts for a bioengineering project by initiating project directions, setting timelines, and providing summaries to a cross-functional team of scientists and engineers which led to two first author publications and three publications with other groups.

• Diagnosed and resolved technical issues in research projects and proposed solutions to a team of 8 members within and across 3 different departments: bioengineering, psychology, and UCR MRI Center.

• Conducted quality assurance tests on a statistical model to ensure it met reliability standards.

• Created SOPs for human neuroimaging data collection and analysis to maintain quality standards and protocols which were executed by 3 team members.

• Catalogued human subject neuroimaging data in accordance with HIPPA and UCR IRB regulations.

• Leveraged SPSS for statistical analyses of sensor-based and human fMRI big data stored in a cloud-based system over a 5-year period to evaluate outcomes and make informed decisions.

• Directed the application of an individually designed Matlab- and Python-based preprocessing pipeline to research projects amongst 2 other collaborators.

• Authored and vetted oral and written technical reports detailing research findings, and presented them to principle investigators, at conferences, and in peer-reviewed publications.

• Perused relevant publications to make informed, up-to-date research decisions, and to generate new project directions.

• Maintained thorough documentation of data analysis, research results, project plans, and project reports.

• Provided leadership and technical consultation to cross-functional teams regarding experimental results and data analyses methods that were consistent with project directions. 

• Developed a hidden Markov model demonstrating the impact of a perturbation in the locus coeruleus circuit on attention networks during resting state. 

• Formulated detailed and organized notes about current and past project findings. 

• Created functional connectivity and BOLD signal profiles on fMRI big data (humans and rats).

• Operated on various software to pre-process and model fMRI and pupillometry data.

• Coached lab members with data pre-processing and analysis.

• Acquired robust interpersonal and presentation skills within and across lab communities.

• Operated on various large data sets: functional MRI and pupillometry data collected at UCR CAN, functional MRI acquired from HCP database.

• Established reliable methods of DNA transcription and mRNA translation so that proteins expressed from engineered genes could be reliably analyzed.

• Surveyed the complexity and content of transcribed RNA libraries used for next generation sequencing.

• Implemented various wet-lab provedures: Qubit quantification, Nanodrop quantification, AMPure bead purification, (q)PCR, western blots, gel electrophoresis.

• Performed bacterial cloning and cell culture maintenance .

• Engaged in a senior design project titled "Modeling the Human Placenta in Vitro".

• Bioprinted cells onto a scaffold to create an in vitro model of a placenta that employs fluid, nutrient, and drug transport.

• Successfully engineering a fundamental in vitro placental construct.

• Collaborated with three other students and two professors in order to complete the lab work and to author technical reports.

• https://invitroplacentamodel.wixsite.com/placentamodel 

University of California, Riverside, Department of Bioengineering

Sept. 2016 - Sept. 2021

Advisers: Dr. Xiaoping Hu (xhu@engr.ucr.edu) and Dr. Megan A.K. Peters (megan.peters@uci.edu)

Dissertation Title: Exploring Hidden Markov Models in Human Functional Magnetic Resonance Imaging Data With Applications to the Locus Coeruleus Circuit (Dissertation; Defense Slides)

University of California, Riverside, Department of Bioengineering

Sept. 2016 - Jun. 2018

Advisers: Dr. Xiaoping Hu and Dr. Megan Peters

University of California, San Diego, Department of Bioengineering

Sept. 2012 - Jun. 2016