Research Interests

Dr. Dharmendra Kumar Yadav research interest includes in computer simulations on the plasma chemistry inside the plasma jet, and its interaction with liquid medium, by 0D chemical kinetics models and 2D fluid models, as well as on the interaction of reactive plasma species with biomolecules, like DNA, proteins and phospholipids in the plasma membrane of cells, by means of molecular dynamics simulations or DFT-based methods, to better understand the underlying mechanisms of plasma medicine, in order to be able to improve the applications. We also interested in plasma medicine, focusing mainly on plasma for cancer treatment. We perform experiments with a plasma jet on various types of cancer cells, both by direct treatment and indirect treatment by plasma activated medium. These experiments are in collaboration with the groups Kwangwoon University (EH. Choi, Director of Plasma Bioscience Research Center/PDP Research Center). We also intersted in developing novel in silico predictive QSAR models for genome/proteome wide identification of functionally conserved DNA and protein motifs through application of statistical and machine learning approaches.

Current Area of Research

My expertise is in developing novel in silico predictive QSAR models for genome/proteome wide identification of functionally conserved DNA and protein motifs through application of statistical and machine learning approaches. I am studying on plasma chemistry using computer modelling for various applications mainly focus on plasma medicine for cancer treatment. Our research activities comprise the study of plasma and plasma-surface interactions by means of computer modeling and experiments, for various applications, i.e., CO2 and N2, H2O, H2, H2O2, and N2 conversion into value-added chemicals and fuels, plasma medicine, nanotechnology. Its interaction with reactive plasma species with biomolecules, like DNA, proteins and phospholipids in the plasma membrane of cells, by means of molecular dynamics simulations or DFT-based methods, to better understand the underlying mechanisms of plasma medicine, in order to be able to improve the applications.