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Funding

The Jenne Lab is supported by the following funding sources:



Current Support 
 


 
Canada Research Chair, Tier II

 Imaging Approaches Towards Studying Infection

 
Canadian Foundation for Innovation, John R. Evans Leaders Fund - Intravital Imaging of Viral and Bacterial Infections: Supports the purchase, development and maintenance of advanced imaging infrastructure for the study of highly pathogenic infectious organisms.

 
New Frontiers in Research Fund (NFRF)
(Co-applicants Dr. Carla Coffin and Dr. Doug Mahoney 
[U of C]; Dr. Zania Stamataki [University of Birmingham]) - Advanced Microscopic Imaging of Living Human Liver: Support to build live human tissue perfusion and imaging infrastructure.
 

Heart and Stroke Foundation of Canada (HSFC) Grant-in-aid – The Role of Platelet Activation in Pathogen-induced Coagulopathy:
Research funding to study the impact of intravascular infection and the resulting immune response on platelet activation, coagulation, blood flow and tissue health 
 

Canadian Institutes of Health Research Canadian 2019 Novel Coronavirus (2019-nCoV) Rapid Research Grant  (Collaborator with Dr. Parsons Leigh, Dr. Fiest, Dr. Fowler, Ms. Foster, Ms, Kupsch, Ms Longmore, Dr. Stelfox, Dr. Straus) - Socio-Cultural Implications of COVID-19: Educating, Engaging & Empowering the Public: This project will help develop strategies to combat misinformation, stigma, and fear related to COVID-19. By engaging the Canadian public we will develop a strategic approach to address the underlying drivers, improve public awareness, knowledge, and trust. This approach will involve local perspectives, citizens, and communities in the COVID-19 response effort.


 Canadian Institutes of Health Research Canadian 2019 Novel Coronavirus (2019-nCoV) Rapid Research Grant (Co-Applicant with Dr. Hobman, Dr. Evans, Dr. Julien, Dr. Victoria Ansalem, Dr. Czub, Dr. van Marle,    Dr. Nagata) - Therapeutic approaches to SARS-CoV-2 and other pathogenic coronaviruses: This project will help explore novel antiviral therapies and novel vaccine approaches to treat and prevent COVID-19 resulting from infection with SARS-CoV-2.
 

Canadian Institutes of Health Research Canadian 2019 Novel Coronavirus (2019-nCoV) Rapid Research Grant (Co-Applicant with Dr. Bell, Dr. Ilkow, Dr. Lapointe, Dr.  Mahoney, Dr. Angel, Dr. Auer, Dr. Bohm, Dr. Cailhier, Dr. Cameron, Dr. Diallo, Dr. Jamison, Dr. Russell-Ladrigue Development of Vaccines to Prevent SARS-CoV-2 Infection of High-Risk Individuals: This project will develop a virus-delivered COVID-19 vaccine platform. Studies will take advantage of the new BSL3 facility in Calgary to directly assess the efficacy of these novel vaccine strategies.
 

Canadian Institutes of Health Research Canadian 2019 Novel Coronavirus (2019-nCoV) Rapid Research Grant
 
(Co-Applicant with Dr. Kubes, Dr. Corcoran, Dr. Gillrie, Dr.  Mody, Dr. Kelly, Dr. McDonald, Dr. Peters Imaging COVID-19 Lungs to Uncover TherapiesThis project will utilize a mix of experimental approaches within the BSL3 facility at the University of Calgary to map mechanisms of the host immune response and viral pathology. 
 

Canadian Institutes of Health Research Project Grant (Co-applicant with Dr. Doug Mahoney) – Mechanisms Underlying Oncolytic Rhabdovirus-mediated Anti-cancer ImmunityResearch funding to support the development and delivery of oncolytic viruses as an immunotherapy for the treatment of cancer.
 
Natural Science and Engineering Research Council of Canada (NSERC) Discover Grant - Development of Imaging Approaches to Study Coagulation In Vivo: Research funding to develop a multifunctional imaging platform and novel fluorescent probes to study coagulation in live animals, in real-time
 

The Lung Association of Alberta & NWT National Grant Review -  Role of tissue factor in the initiation of inflammation in response to Influenza A virus infection: Research funding to understand the role of tissue factor in a mouse model of highly pathogenic H1N1 influenza infection.
University of Calgary Margaret Gunn Endowment for Animal Research (MGEAR) - Intravital Microscopy of the Immune Response to Influenza Infection in Chickens: Research funding to understand how influenza and the immune system interact and cause disease in chickens in an effort to development better animal vaccines and treatments.

 

Women in Insurance Cancer Crusade - Intravital Microscopy and Cancer:
Research funding to support studies using intravital microscopy to study oncolytic virus-based immunotherapies for the treatment of cancer.
 


Trainee Support


Beverley Phillips Rising Star Postdoctoral Fellowship - Using intravital microscopy to track viral delivery, infection and clearance in a mouse model of gene therapy: This fellowship helped facilitate the recruitment of Agostina Carestia from Argentina to join our research team in Calgary 
 

The University of Calgary, Cumming School of Medicine Postdoctoral Scholar Program - Using intravital microscopy to track viral delivery, infection and clearance in a mouse model of gene therapy: 
This fellowship helped facilitate the recruitment of Agostina Carestia from Argentina to join our research team in Calgary 



   University of Calgary Eyes High Doctoral Scholarship – The role of viral infection in leukocyte recruitment during oncolytic virus therapy:
 This studentship allowed the recruitment of Madison Turk from the University of Western Ontario to join our research team in Calgary.

The NSERC Alexander Graham Bell ScholarshipThis Scholarship was award to Madison Turk to support her studies focused on the use of oncolytic viruses as an immunotherapy to treat cancer.
 

Metis Education Foundation Scholar Award –  Investigating the immune response to viral infection in the context of non-alcoholic fatty liver disease: This studentship was awarded to Rachelle Davis


Alberta Graduate Excellence Scholarship (AGES) - Doctoral Research Award - Investigating the immune response to viral infection in the context of non-alcoholic fatty liver disease (NAFLD)
This studentship was awarded to Rachelle Davis





Past Support

Canadian Cancer Society Research Institute (CCSRI) Innovation Grant (Co-PI with Dr. Douglas Mahoney) - Understanding oncolytic virus delivery using intravital imaging: Research funding to study how oncolytic viruses “find” and infect tumours and how these viruses may interact with leukocytes within the bloodstream and the tumour. 

Critical Care Strategic Clinical Network – The Role of Platelets and Neutrophil Extracellular Traps (NETS) in Disseminated Intravascular Coagulation (DIC): Research support to study how immune effector molecules (NETS) directly interact with and platelets leading to infection-induced coagulopathy. 
 

 
CIHR Operating Grant: Innovative Ebola Research Grants – Ebola Biology –  Deciphering the signaling mechanisms underlying Ebola virus-mediated inflammatory response upon interaction/entry with human macrophages (collaborator, grant PI is Dr. Marceline Cote): Research support to study in vivo how viral particles are captured and processed as a basis for the development of viral vaccine vectors. 
 
CIHR Industry-Partnered Collaborative Research Grant: Pathogenesis of Hepatitis B Virus Infection in Non-Alcoholic Fatty Liver Disease (Co-Applicant with Dr. Carla Coffin and Dr. Saumya Jayakumar; Partnered with GlaxoSmithKline): Research funding to study Hep B pathogenesis, immune function and vaccination efficiency in patients with non-alcoholic fatty liver disease. 
 
Critical Care Strategic Clinical Network – Identification of a bioprofile in children with appendicitis who have severe disease requiring PICU (collaborator, grant PI is Dr. Jamie Blackwood): Research support for a clinical study looking to identify a protein/metabolite “fingerprint” that will help identify children with severe appendicitis 
 

The Lung Association of Alberta & NWT National Grant Review - Role of intravascular thrombin on platelet activation and lung inflammation during Influenza A virus infection: Research funding to understand the role of thrombin generation and platelet activation during a mouse model of highly pathogenic flu infection. 
 
University Research Grants Committee (URGC) Faculty Seed Grant - Mapping the host inflammatory response to highly pathogenic influenza A infection: Research funding to develop a lung model of highly pathogenic H1N1 infection for intravital imaging in mice 

 
Cumming School of Medicine Office of the Associate Dean Research (OADR) Bridge Funding - Interaction between inflammation, immunity and coagulation in highly pathogenic influenza infection: Research funding to develop a lung model of highly pathogenic H1N1 infection for intravital imaging in mice 

 

Canadian Liver Foundation Graduate Studentship - Assessing the efficacy of hepatitis B vaccination in the context of non-alcoholic fatty liver disease: This studentship was awarded to Rachelle Davis 
 
University of Calgary Faculty of Graduate Studies Indigenous Graduate Award  –  Investigating the immune response to viral infection in the context of non-alcoholic fatty liver disease (NAFLD)This studentship was awarded to Rachelle Davis 
 
University of Calgary Faculty of Graduate Studies Queen Elizabeth II Graduate Scholarship  –  Mechanisms of Oncolytic Virus-Mediated Vascular Collapse: This studentship was awarded to Rachelle Davis. 
 
  
  
  
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