Phytosomes

http://www.ijpsr.com/V2I4/10%20Vol.%202,Issue%204,IJPSR,2011,Review%2010.pdf

The bioavailability of some orally administered botanical extracts is erratic and poor due to limited gastro-intestinal  absorption. Bioavailability can be improved by using new  delivery systems which can enhance the rate and the extent  of solubilization into aqueous intestinal fluids and the
capacity to cross biomembranes. Phospholipids based drug  delivery system have been found promising for better and  effective delivery of drug and providing much appropriate  systematic drug delivery. The phospholipids molecular  structure includes a water-soluble head and two fat-soluble
tails, because of this dual solubility, the phospholipids acts as an effective emulsifier, which is also one of the chief  components of the membranes in our cells. 
In other words, complexing the polyphenolic phytoconstituents in molar ratio with phosphatidylcholine results into a new herbal drug delivery system- "Phytosome". Phytosomes are an advanced botanicals technology that offers improved absorption, enhanced delivery and increased bioavailability of herbal extracts. Phytosomes exhibit better pharmacokinetic and pharmacodynamic profile than conventional herbal extracts
Phytosome technology has been effectively used to enhanced the bioavailability of many popular herbal extracts including milk thistle, Ginkgo bilobann, grape seed, green tea, hawthorn, ginseng etc and can be developed for various therapeutic uses or dietary supplements This article reviews
the current trends in phytosomes drug delivery.

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