Title: Understanding Complex Biochemical Pathways and Identification of Drug Targets                                       

AbstractHistorically human population is under threat of different diseases, which eventually led to discovery of drugs/medicines for better treatment and cure. With the advent of science and technology drug research, mostly depending on chemistry and biology, became an interdisciplinary endeavor with an industrial base. Moreover, the traditional approaches that have prevailed in drug discovery have resulted in failure of many promising drug candidates in the last few decades. Though in recent years, we have gained significant understanding about the diseases, but still the lack of understanding of the complex biological processes and lack of knowledge about biochemical pathways often led to unforeseen adverse effects as well as unacceptable toxicity profiles. In this talk, I will discuss these perspectives comparing the traditional and modern methods of drug discovery and will present few stories related to the drug target identification, the works we are continuing in our group.