Recent Publications


Jha, A. K., Jackson, W. M. & Healy, K. E. Controlling osteogenic stem cell differentiation via soft bioinspired hydrogels. PLoS One 9, e98640 (2014).

Vazin, T. et al. The effect of multivalent Sonic hedgehog on differentiation of human embryonic stem cells into dopaminergic and GABAergic neurons. Biomaterials 35, 941–8 (2014).

Yum, K., Hong, S. G., Healy, K. E. & Lee, L. P. Physiologically relevant organs on chips. Biotechnol. J. 9, 16–27 (2014).

Ma, Z. et al. Three-dimensional filamentous human diseased cardiac tissue model. Biomaterials 35, 1367–77 (2014).

Spencer, C. I. et al. Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia. Stem Cell Reports 3, 269–281 (2014).


Conway, A. et al. Multivalent ligands control stem cell behavior in vitro and in vivo. Nat. Nanotechnol. 8, 831–8 (2013).

Mathur, A. et al. Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development. Stem Cell Res. Ther. 4 Suppl 1, S14 (2013).

Healy, K. E., McDevitt, T. C., Murphy, W. L. & Nerem, R. M. Engineering the emergence of stem cell therapeutics. Sci. Transl. Med. 5, 207ed17 (2013).

Schmidt, R. C. & Healy, K. E. Effect of avidin-like proteins and biotin modification on mesenchymal stem cell adhesion. Biomaterials 34, 3758–62 (2013).


Pollock, J. F., Ashton, R. S., Rode, N. A., Schaffer, D. V & Healy, K. E. Molecular characterization of multivalent bioconjugates by size-exclusion chromatography with multiangle laser light scattering. Bioconjug. Chem. 23, 1794–801 (2012).


Jeon, H. et al. Chemical patterning of ultrathin polymer films by direct-write multiphoton lithography. J. Am. Chem. Soc. 133, 6138–41 (2011).

Irwin, E. F., Gupta, R., Dashti, D. C. & Healy, K. E. Engineered polymer-media interfaces for the long-term self-renewal of human embryonic stem cells. Biomaterials 32, 6912–9 (2011).

Little, L. E., Dane, K. Y., Daugherty, P. S., Healy, K. E. & Schaffer, D. V. Exploiting bacterial peptide display technology to engineer biomaterials for neural stem cell culture. Biomaterials 32, 1484–94 (2011).


Saha, K. et al. Surface creasing instability of soft polyacrylamide cell culture substrates. Biophys. J. 99, L94–6 (2010).

Wall, S. T., Yeh, C.-C., Tu, R. Y. K., Mann, M. J. & Healy, K. E. Biomimetic matrices for myocardial stabilization and stem cell transplantation. J. Biomed. Mater. Res. A 95, 1055–66 (2010).

Ananthanarayanan, B., Little, L., Schaffer, D. V, Healy, K. E. & Tirrell, M. Neural stem cell adhesion and proliferation on phospholipid bilayers functionalized with RGD peptides. Biomaterials 31, 8706–15 (2010).

Keung, A. J., Healy, K. E., Kumar, S. & Schaffer, D. V. Biophysics and dynamics of natural and engineered stem cell microenvironments. Wiley Interdiscip. Rev. Syst. Biol. Med. 2, 49–64 (2010).

Su, J., Wall, S. T., Healy, K. E. & Wildsoet, C. F. Scleral reinforcement through host tissue integration with biomimetic enzymatically degradable semi-interpenetrating polymer network. Tissue Eng. Part A 16, 905–16 (2010).


Healy, K. E. Patterning: Cells nourished by nanodrops. Nat. Mater. 8, 700–2 (2009).

Kohen, N. T., Little, L. E. & Healy, K. E. Characterization of Matrigel interfaces during defined human embryonic stem cell culture. Biointerphases 4, 69–79 (2009).


Wall, S. T. et al. Multivalency of Sonic hedgehog conjugated to linear polymer chains modulates protein potency. Bioconjug. Chem. 19, 806–12 (2008).


Saha, K., Irwin, E. F., Kozhukh, J., Schaffer, D. V & Healy, K. E. Biomimetic interfacial interpenetrating polymer networks control neural stem cell behavior. J. Biomed. Mater. Res. A 81, 240–9 (2007).

Patel, S., Tsang, J., Harbers, G. M., Healy, K. E. & Li, S. Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers. J. Biomed. Mater. Res. A 83, 423–33 (2007).

Ho, J. E., Barber, T. A., Virdi, A. S., Sumner, D. R. & Healy, K. E. The effect of enzymatically degradable IPN coatings on peri-implant bone formation and implant fixation. J. Biomed. Mater. Res. A 81, 720–7 (2007).


Wall, S. T., Walker, J. C., Healy, K. E., Ratcliffe, M. B. & Guccione, J. M. Theoretical impact of the injection of material into the myocardium: a finite element model simulation. Circulation 114, 2627–35 (2006).


Healy, K. E. Control of cell function with tunable hydrogel networks. Conf. Proc.  ... Annu. Int. Conf. IEEE Eng. Med. Biol. Soc. IEEE Eng. Med. Biol. Soc. Annu. Conf. 7, 5035 (2004).

SelectionFile type iconFile nameDescriptionSizeRevisionTimeUser

  Aug 1, 2012, 1:08 PM Healy Lab