Restart your laptop regulary rather than just shutting the lid or clicking "shut down". Restarting your laptop applies nessecary updates.
A program called Dell Command Update will periodically prompt you to install updates or restart your computer to install updates. Install these updates when prompted.
Charge your computer each night!
Always use the provided laptop sleeve when transporting your computer. You may decide to purchase a more protective case for your computer.
Avoid eating and drinking near your laptop.
A detailed list of best practices from CCPS Technology Services can be found HERE